Cardiopulmonary protection in severe respiratory disease

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Disease-modifying biologic therapies have transformed long-term outcomes in patients with severe asthma and COPD: This review considers their value and the need for cardiopulmonary protection in all these patients

Learning objectives

You will learn:

  • Real and potential impacts of disease-modifying biologic therapies on clinical outcomes in severe respiratory disease
  • Proposed new criteria for clinical definitions of asthma remission and the efficacy of biologics that target T2/eosinophilic inflammation or epithelial alarmins in severe asthma
  • Insight into cardiopulmonary risk driven by chronic obstructive pulmonary disease exacerbations and clinical/real-world evidence guiding current approaches to pharmacotherapy.

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