Clinical Update – Upper GI bleeding and gastroprotection in very high-risk patients

You will learn:
• Protein pump inhibitors (PPI’s) are invaluable and very effective agents used for the management of gastrointestinal (GI) acid-related disorders¹
• While PPI’s are the cornerstone of gastroesophageal reflux disease (GERD) treatment, 40% of patients do not derive full symptom relief with these agents²
• Better results can be achieved by selecting a particular PPI for each GERD-confirmed patient based on that PPI’s pharmacokinetic, pharmacogenomic and antioxidant actions 
• New data showing that some PPIs have potent antioxidant properties create an opportunity to provide a dual-action protective role in very high-risk patients
• Upper GI bleeding is a major health problem and the definition of groups at high risk for developing peptic ulcer complications helps to prioritise the provision of PPI therapy