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MAKING BEST PRACTICE, EVERYDAY PRACTICE

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GLP-1 Receptor Agonists (GLP-1RAs): Extending access to more T2DM patients with chronic obesity

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Question 1 of 10
1. Question
The most common cause of mortality in South African females is:
A. HIV/AIDS
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B. Tuberculosis
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C. Diabetes
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D. Breast cancer
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Question 2 of 10
2. Question
The GLP-1 RA that is most homologous to native GLP-1 is:
A. Exenatide
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B. Liraglutide
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C. Semaglutide
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D. Dulaglutide
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Question 3 of 10
3. Question
GLP-1RAs exert direct physiological effects on the:
A. Pancreas, liver and muscle
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B. Liver, stomach and adipose tissue
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C. Liver, adipose tissue and brain
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D. Pancreas, brain and stomach
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Question 4 of 10
4. Question
Compared to men, the risk of developing diabetes in women is more than double when BMI exceeds:
A. 25kg/m2
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B. 27kg/m2
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C. 28kg/m2
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D. 30kg/m2
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Question 5 of 10
5. Question
Significant weight loss at one year was demonstrated in participants of the SCALE Diabetes trial who received:
A. Liraglutide 1.8mg
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B. Liraglutide 3.0mg
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C. Both of the above
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D. Neither of the above
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Question 6 of 10
6. Question
Fewer than 20% of patients with T2DM achieve ‘ABC’ control, which is a composite of glycaemic, blood pressure and LDL-C targets.
A. True
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B. False
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Question 7 of 10
7. Question
South African data report that in both private and public health sectors and across primary to tertiary healthcare, only half of patients with T2DM achieve HbA_1c <7%.
A. True
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B. False
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Question 8 of 10
8. Question
The percentage of liraglutide-treated participants of the LEAD programme who achieved HbA_1c <7% was:
A. 15-25%
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B. 30-40%
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C. 50-60%
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D. 75-85%
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Question 9 of 10
9. Question
In terms of target organ damage, T2DM:
A. Increases the risk for developing HF by two- to five-fold
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B. Increases the probability of cardiovascular death and all-cause mortality by 60-80% in those with established HF
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C. Is associated with atherosclerotic diseases that account for half of CVD mortality
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D. All of the above
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Question 10 of 10
10. Question
Cardiovascular risk factors for which beneficial effects of GLP-1RA therapies have been reported include:
A. SBP, total cholesterol and body weight
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B. Body weight, but not SBP nor total cholesterol
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C. SBP and total cholesterol, but not body weight
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D. Body weight and total cholesterol, but not SBP
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